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Mitochondrial replacement techniques (MRTs) are designed to prevent the transmission of mitochondrial DNA (mtDNA) diseases from mother to child. While MRTs, if effective, could satisfy a desire of women seeking to have a genetically related child without the risk of passing on mtDNA disease, the technique raises significant ethical and social issues. It would create offspring who have genetic material from two women, something never sanctioned in humans, and would create mitochondrial changes that could be heritable (in female offspring), and therefore passed on in perpetuity. The manipulation would be performed on eggs or embryos, would affect every cell of the resulting individual, and once carried out this genetic manipulation is not reversible. Mitochondrial Replacement Techniques considers the implications of manipulating mitochondrial content both in children born to women as a result of participating in these studies and in descendants of any female offspring. This study examines the ethical and social issues related to MRTs, outlines principles that would provide a framework and foundation for oversight of MRTs, and develops recommendations to inform the Food and Drug Administration’s consideration of investigational new drug applications. Find a Supervisor /PhD Project - NUI Galway One of the most important parts of choosing a research programme is finding a supervisor who has relevant expertise in your area of interest. When you find a ... Resolve a DOI Name Type or paste a DOI name into the text box. Click Go. Your browser will take you to a Web page (URL) associated with that DOI name. Send questions or comments to doi ... Welcome to Orca Network - Field Studies Top of Page Next Ainley David G. Grant Ballard and Silvia Olmastroni. 2009. An Apparent Decrease in the Prevalence of "Ross Sea Killer Whales" in the Southern ... A-Z and glossary - Open Policy Making toolkit - Guidance ... This manual includes information about Open Policy Making as well as the tools and techniques policy makers can use to create more open and user led policy. Ethical issues in Health care List of High Impact ... The Australian Health Ethics Committee is concerned with the ethical suggestions of medical research and practice and of health care in general Ethics are social ... CRISPR germline engineering[mdash]the community speaks ... Nature Biotechnology asks selected members of the international community to comment on the ethical issues raised by the prospect of CRISPR-Cas9 engineering of the ... Genome editing and stem cells: Questions and Answers ... Genome editing has been around in a number of forms for decades. The first generation was based on molecular scissors such as ZNFs and TALENS that could make ... Doctoral Dissertations Available from Proquest ... Submissions from 2014. Amoroso Jon William (2014) Reactive Probes for Manipulating Polyketide Synthases and Photoreactive Probes for Strained Alkyne Click Chemistry American Journal of Psychiatry Residents' Journal October 2015 Residents' Journal. Transcranial Direct Current Stimulation: Theory Treatment of Major Depressive Disorder and Other Neuropsychiatric Applications by ... BibMe: Free Bibliography & Citation Maker - MLA APA ... Using other peoples research or ideas without giving them due credit is plagiarism. Since BibMe makes it easy to create citations build bibliographies and ...
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